Extrapleural Pneumonectomy

Extrapleural pneumonectomy (EPP) is a radical surgery used to treat pleural mesothelioma.  The goal of EPP is to remove the entire mesothelioma tumor from the body.  The thoracic surgeon will remove an entire lung and lymph nodes on one side, as well as part of the pleura and diaphragm.  Often the pericardial lining of the heart is removed as well.  The diaphragm and pericardium are then reconstructed with an artificial material.

EPP is most often used in the early stages of mesothelioma when the cancer is still localized.  This type of surgery is most successful when it is combined with other treatments such as radiation or chemotherapy.

EPP is a very difficult operation, and should only be performed by an expert surgeon.  Patients must be in good physical shape to tolerate the procedure.  The recovery is long and painful, and there can be major complications.  However, if your doctor tells you that you are a good candidate for surgery, an EPP may offer the best chance of complete tumor removal.